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Zerafil Dosing
Response Assessment
Response Assessment: Asthma
Response Assessment: Urticaria
Response Assessment: CRSwNP
Treatment Initiation
Treatment Initiation: Asthma
Treatment Initiation: Urticaria
Treatment Initiation: CRSwNP
Control Test
Control Test: Asthma (ACT)
Control Test: Urticaria (UCT)
Control Test: Sino-Nasal Outcome Test (SNOT-22)
Zerafil Dosing
Response Assessment
Response Assessment: Asthma
Response Assessment: Urticaria
Response Assessment: CRSwNP
Treatment Initiation
Treatment Initiation: Asthma
Treatment Initiation: Urticaria
Treatment Initiation: CRSwNP
Control Test
Control Test: Asthma (ACT)
Control Test: Urticaria (UCT)
Control Test: Sino-Nasal Outcome Test (SNOT-22)
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SNOT-22
Sino-Nasal Outcome Test (SNOT-22)
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SNOT-22 is a 22-item health-related quality of life (HRQoL) evaluation with each item scored on a Likert scale ranging from 0 (“No problem”) to 5 (“Problem as bad as it can be”). On this global 110-point scale, a change in score of 8.9 is the smallest change that is considered clinically important, corresponding to the validated minimal clinically important difference defined by the developer.
Please score each of the following items for this patient, considering both symptom severity and frequency.
No problem = 0
Very mild problem = 1
Mild or slight Problem = 2
Moderate problem = 3
Severe problem = 4
Problem as bad as it can be = 5
Need to blow nose
*
No problem
Very mild problem
Mild or slight Problem
Moderate problem
Severe problem
Problem as bad as it can be
Nasal Blockage
*
No problem
Very mild problem
Mild or slight Problem
Moderate problem
Severe problem
Problem as bad as it can be
Sneezing
*
No problem
Very mild problem
Mild or slight Problem
Moderate problem
Severe problem
Problem as bad as it can be
Runny nose
*
No problem
Very mild problem
Mild or slight Problem
Moderate problem
Severe problem
Problem as bad as it can be
Cough
*
No problem
Very mild problem
Mild or slight Problem
Moderate problem
Severe problem
Problem as bad as it can be
Post-nasal discharge
*
No problem
Very mild problem
Mild or slight Problem
Moderate problem
Severe problem
Problem as bad as it can be
Thick nasal discharge
*
No problem
Very mild problem
Mild or slight Problem
Moderate problem
Severe problem
Problem as bad as it can be
Ear fullness
*
No problem
Very mild problem
Mild or slight Problem
Moderate problem
Severe problem
Problem as bad as it can be
Dizziness
*
No problem
Very mild problem
Mild or slight Problem
Moderate problem
Severe problem
Problem as bad as it can be
Ear pain
*
No problem
Very mild problem
Mild or slight Problem
Moderate problem
Severe problem
Problem as bad as it can be
Facial pain/pressure
*
No problem
Very mild problem
Mild or slight Problem
Moderate problem
Severe problem
Problem as bad as it can be
Decreased Sense of Smell/Taste
*
No problem
Very mild problem
Mild or slight Problem
Moderate problem
Severe problem
Problem as bad as it can be
Difficulty falling asleep
*
No problem
Very mild problem
Mild or slight Problem
Moderate problem
Severe problem
Problem as bad as it can be
Wake up at night
*
No problem
Very mild problem
Mild or slight Problem
Moderate problem
Severe problem
Problem as bad as it can be
Lack of a good night’s sleep
*
No problem
Very mild problem
Mild or slight Problem
Moderate problem
Severe problem
Problem as bad as it can be
Wake up tired
*
No problem
Very mild problem
Mild or slight Problem
Moderate problem
Severe problem
Problem as bad as it can be
Fatigue
*
No problem
Very mild problem
Mild or slight Problem
Moderate problem
Severe problem
Problem as bad as it can be
Reduced productivity
*
No problem
Very mild problem
Mild or slight Problem
Moderate problem
Severe problem
Problem as bad as it can be
Reduced concentration
*
No problem
Very mild problem
Mild or slight Problem
Moderate problem
Severe problem
Problem as bad as it can be
Frustrated/restless/irritable
*
No problem
Very mild problem
Mild or slight Problem
Moderate problem
Severe problem
Problem as bad as it can be
Sad
*
No problem
Very mild problem
Mild or slight Problem
Moderate problem
Severe problem
Problem as bad as it can be
Embarrassed
*
No problem
Very mild problem
Mild or slight Problem
Moderate problem
Severe problem
Problem as bad as it can be
SUM
Overview of the Algorithms